National Academy of Medicine Archives - healthylongevitychallenge.org

Eliminating mutated mitochondrial DNA with modified nucleic acids

Joseph Baur, PhD| University of Pennsylvania
Competition Sponsor: US National Academy of Medicine
Awardee Year: 2022 Mitochondria, the “powerhouses of the cell” contain their own genomes that are present in hundreds of copies per cell and are prone to mutation. Over the course of aging, some cells end up with…

Catalyst Awardee

Granulocyte Colony Stimulating Factor: A Novel Agent for Reproductive Longevity and Equality

Leslie Coker Appiah, MD| The University of Colorado Anschutz Medical Campus; Benjamin Bitler, PhD

Competition Sponsor: US National Academy of Medicine
Awardee Year: 2022

Advancements in cancer therapies have resulted in a sharp reduction in cancer mortality rates. However, lifesaving cancer treatments can jeopardize a woman’s reproductive longevity and impair

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Catalyst Awardee

Rebuilding the Health Workforce in Africa to Care for an Aging Population

Dr. Vanessa Kerry, MD, MSc. | Seed Global Health

Competition Sponsor: US National Academy of Medicine
Awardee Year: 2022

Africa’s elderly population is expected to grow faster than in any other region in the world, with a projected threefold increase by 2050. An aging population is accompanied by a shift

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Catalyst Awardee

Bridging the Gap between Postpartum and Primary Care: Novel Approaches to Care Continuity for Women at High Risk for Chronic Disease

Jessica Cohen, PhD | Harvard T. H. Chan School of Public Health; Mark Clapp, MD, MPH | Massachusetts General Hospital and Harvard Medical School

Competition Sponsor: US National Academy of Medicine
Awardee Year: 2022

Primary care providers (PCPs) are essential for prevention and management of chronic diseases across the lifespan.

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Catalyst Awardee

Development of a next-generation pharmaceutical to target oxidized cholesterol and reverse cardiovascular disease

Matthew S. O’Connor, PhD | Cyclarity Therapeutics

Competition Sponsor: US National Academy of Medicine
Awardee Year: 2022

Toxic oxysterols have been tied to numerous age-related diseases. Our team of scientists has engineered a custom cyclodextrin (a cyclic polysaccharide), which is designed to extract these toxic biomolecules from the body. We

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Catalyst Awardee

Exercise and Brain Health: Pre-clinical Study of the Energy Transfer Hypothesis of Aging using PET/MRI imaging

Lauren Gerard Koch, PhD | The University of Toledo; Xin Yu, Sc.D. | Case Western Reserve University; Steven L. Britton, Ph.D. | University of Michigan
Competition Sponsor: US National Academy of Medicine
Awardee Year: 2022 There is a strong link between high aerobic energy capacity and the increase in…

Catalyst Awardee

Expanding a Multimodality VR Fitness Platform to Remotely Assess, Monitor, and Report Cognitive and Physical Function for Seniors

Jennifer J Stamps, PhD | Rendever; Kyle Rand, Co-founder/CEO, BS/BSE | Rendever
Competition Sponsor: US National Academy of Medicine
Awardee Year: 2022 As healthcare costs and the aging population increase, preventing the loss of cognitive and physical function is an urgent initiative. Social isolation increases the risk of…

Catalyst Awardee

Monitoring of Alzheimer’s Disease Pathology Through Slow Wave Activity During Sleep in Older Adults

Makoto Kawai, MD | Division of Sleep Medicine, Department of Psychiatry and Behavioral Sciences, School of Medicine
Stanford University; Ada Poon, PhD |Department of Electrical Engineering, Stanford University
Competition Sponsor: US National Academy of Medicine
Awardee Year: 2022 It has been suggested that sleep can provide a…

Catalyst Awardee

Multi-modal Microwave Radar & Electroencephalography-based Brain-Computer Interfaces for Non-Invasive Functional Imaging of the Brain

Emily Porter, PhD | The University of Texas at Austin; Jose del R. Millan, PhD | The University of Texas at Austin
Competition Sponsor: US National Academy of Medicine
Awardee Year: 2022 Brain-computer interfaces (BCIs) have the potential to revolutionize the way we treat brain-related injuries and diseases. To…

Catalyst Awardee

Intergenerational Mentoring to Promote Health Across the Lifespan

Corey A. Nichols-Hadeed, JD | University of Rochester Medical Center; Kiah E. Nyame, EdD | City of Rochester; Kimberly A. Van Orden, PhD | University of Rochester Medical Center; Malik R. Sams, MD | University of Rochester Medical Center
Competition Sponsor: US National Academy of Medicine
Awardee Year:…

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