National Academy of Medicine Archives - Page 2 of 3

The Aging Exposome: Characterizing Bidirectional Effects of Exposures and Aging

Ram Gouripeddi, MBBS, MS; Julio Facelli, PhD | Department of Biomedical Informatics, University of Utah
Competition Sponsor: US National Academy of Medicine
Award year: 2021 Effects of a lifetime of environmental and lifestyle exposures on aging or age-associated diseases are not well understood. Exposures not only directly affect biological pathways…

Catalyst Awardee

Combating Arterial Aging by Engineering the Gut Virome to Transmit Equol Producing Genes

Justyn Jaworski, PhD and Dan Trott, PhD | University of Texas at Arlington
Competition Sponsor: US National Academy of Medicine
Award year: 2021 Advanced age is the major risk factor for cardiovascular disease (CVD), which is one of the leading causes of death in the industrialized world. Vascular aging manifests…

Catalyst Awardee

A multi-sensor wearable system with a personalized AI and multimodal biofeedback to improve balance of older adults at home

Alparslan Emrah Bayrak, PhD,and Antonia Zaferiou, PhD | Stevens Institute of Technology
Competition Sponsor: US National Academy of Medicine
Awardee Yer: 2021 Falls remain a leading cause of morbidity and decreased quality of life in our older adult community. About half of older adult falls occur in the home. In…

Catalyst Awardee

Transformative oral drugs that reverse muscle weakness and aging in older adults

Stan Watowich, PhD; Harshini Neelakantan, PhD | Ridgeline Therapeutics
Competition Sponsor: US National Academy of Medicine
Award year: 2021 Every adult over 40 years old faces the relentless loss of skeletal muscle strength, caused primarily by the inability of aging muscles to regenerate fully. In the elderly, decreased muscle strength…

Catalyst Awardee

Dynamic Signature of Cuffless Blood Pressure and Risk of Subclinical Brain Disease and Dementia

Yuan Ma, PhD; Albert Hofman, MD, PhD | Harvard T. H. Chan School of Public Health
Competition Sponsor: US National Academy of Medicine
Award year: 2021 Dementia is the most common neurodegenerative disease in older people, associated with high disability and dependency. Hypertension is a key player in the vascular…

Catalyst Awardee

Advancing Cardiovascular Monitoring: Long-term, Accessible, Multi-Modal Soft Bioelectronics

Nanshu Lu, PhD; Phillip Tan, BS | University of Texas at Austin
Competition Sponsor: US National Academy of Medicine
Award year: 2021 Cardiovascular disease (CVD) remains the largest cause of death in the world, leading to significant financial and emotional drain. However, current methods of assessing CVD are inadequate: it…

Catalyst Awardee

Identifying Predictive Biomarkers of Effective Immunity in Aging Populations

Wayne Koff, PhD | Human Vaccines Project
Competition Sponsor: US National Academy of Medicine
Awardee Year: 2021 The world is aging at an unprecedented rate, and we are not prepared. By 2050 nearly 1.6 billion people will be over age 65, creating widespread public health challenges. This aging population will…

Catalyst Awardee

Human Activity Recognition to Avoid Fall Related Injuries in the Older Adult Population

Rebecca Tarbert, DPT, Arun Jayaraman, PT, PhD, and Wamis Singhatat, MSBE | ActiveProtective Technologies, Inc
Competition Sponsor: US National Academy of Medicine
Award Year: 2021 One out of four older adults experience a fall each year and falls are the leading cause of death from injury for older adults in…

Catalyst Awardee

Community Brain Health in African American Faith-Based Organizations

Dean Sherzai, MD, PhD | Healthy Minds Initiative
Competition Sponsor: US National Academy of Medicine
Award year: 2021 Alzheimer’s disease is the fastest growing epidemic in the United States. Though the disease has affected every family, certain communities are disproportionately affected. The black community and women are at twice the…

Catalyst Awardee

Transcranial focused ultrasound for enhanced glymphatic-based delivery of antibodies for brain imaging and therapy

Muna Aryal, PhD, and Tyrone Porter, PhD | Loyola University of Chicago
Competition Sponsor: US National Academy of Medicine
Award Year: 2021 We purpose to develop a new strategy for efficient delivery of large-sized agents to a big portion of the brain which is not possible from the existing brain…

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