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Catalyst Awardee

Development of a New Device for Estimating Cognitive Function, with Application to a Remotely Supervised exercise training system

Shizue Masuki, Ph.D., Shinshu University; Hiroshi Nose, Ph.D., M.D., Shinshu University
Competition Sponsor: Japan Agency for Medical Research and Development The goal of this project is to develop a device for estimating cognitive function (CF) from the heart rate (HR) response before everyday voluntary movements. Previously, we developed a…
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Catalyst Awardee

Developing Next Generation Therapy for Age-related Fibrotic Disorders Targeting Secreted Type Pro-fibrotic Protein (A-FiD Research Consortium Study)

Ippei Shimizu, Ph.D., NIigata University
Competition Sponsor: Japan Agency for Medical Research and Development The Aim of this study is to 1) Establish the concept and biomarker of Age-related Fibrotic Disorder (A-FiD), 2) Generate therapies for A-FiD. Here I define A-FiD as disorders including heart failure with preserved ejection fraction(HFpEF),…
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Catalyst Awardee

Development of a Non-invasive Pathological Diagnostic Tool Based on Integrated MRI-microscopic Imaging to Revolutionize Dementia Research

Takashi Hanakawa, Ph.D., M.D., Kyoto University; Nobukatsu Sawamoto, Ph.D. M.D., Kyoto University; Hitoshi Hashimoto, Ph.D., Osaka University
Competition Sponsor: Japan Agency for Medical Research and Development Cure for dementia is yet to be available despite of the past investment and effort, prompting us to think out of the box. To…
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Catalyst Awardee

Development of a Novel Alzheimer’s Disease Treatment Method by a Unique Brain Proteinderived Peptide with an Advanced Transdermal Absorption Device

Yasoumi Ouchi, Ph.D., M.D., Hamamatsu University; Toshiharu Suzuki, Ph.D., Hokkaido University
Competition Sponsor: Japan Agency for Medical Research and Development While many medical trials such as antibody therapies for amyloid to combat Alzheimer’s disease (AD) are still in vain due to a difficulty in curing the disease, a new drug…
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Catalyst Awardee

Development of Personalized-prognosis Prediction for Pneumonia Including COVID-19 Using Artificial Intelligence

Kazuki Taoka, Ph.D., M.D., The University of Tokyo; Idan Yelin, Ph.D., Israel Institute of Technology
Competition Sponsor: Japan Agency for Medical Research and Development In the present project, the artificial intelligence-based system for assessing pneumonia in the elderly which was previously developed by the principal investigator would be adapted to…
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Catalyst Awardee

Development of a Risk-estimation System for Alzheimer’s Disease Using Blood-based Biomarkers

Akinori Nakamura, Ph.D., M.D., National Center for Geriatrics and Gerontology; Naoki Kaneko, Ph.D., M.D., Shimadzu Corporation; Kenji Ishii, Ph.D., M.D., Tokyo Metropolitan Institute of Gerontology; Kazunari Ishii, Ph.D., M.D., Kindai University; Kengo Ito, Ph.D., M.D., National Center for Geriatrics and Gerontology; Takashi Kato, Ph.D., M.D., National Center for Geriatrics and…
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Catalyst Awardee

Elucidating the Mechanism of Action of Antidepressants by Generation and Sharing of Whole-brain Neurotransmitter Atlas

Yukki Sugiura, Ph.D., Keio University; Eiji Sugiyama, Ph.D., University of Shizuoka
Competition Sponsor: Japan Agency for Medical Research and Development The mechanism of antidepressants is still not clear despite the growing number of patients with psychiatry diseases. Such a knowledge gap made patients suffering from ineffective medicine as well as…
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