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Catalyst Awardee

Role of Cardiomyocyte Turnover on Age-related Cardiovascular Diseases

Wataru Kimura, Ph.D., RIKEN Center for Biosystems Dynamics Research; Osamu Yamguchi, M.D., Ph.D., Ehime University Graduate School of Medicine; Kinya Otsu, M.D., Ph.D., Osaka University Graduate School of Medicine; Manabu Taneike, M.D., Ph.D., Osaka University Graduate School of Medicine; Masumoto Hidetoshi, M.D., Ph.D., RIKEN Center for Biosystems Dynamics Research
Competition…

Catalyst Awardee

Role of the Hypothalamus in Mammalian Aging/Longevity Through the Regulation of sleep Quality

Akiko Satoh, Ph.D., National Center for Geriatrics and Gerontology
Competition Sponsor: Japan Agency for Medical Research and Development This study aims to elucidate the physiological function of PRDM13-positive neurons in the dorsomedial hypothalamus, and the molecular mechanisms by which PRDM13-positive neurons regulate sleep quality, and systemic phenomena sequentially occurring with…

Catalyst Awardee

Search for Determinants of Cognitive Resilience in Old Age

Takamitsu Watanabe, Ph.D., M.D., The University of Tokyo; Akin Ojabemi, Ph.D., University of Ibadan; Carolyn Parsey, Ph.D., University of Washington
Competition Sponsor: Japan Agency for Medical Research and Development Population aging has been increasing the global prevalence of dementia, whose impacts are overwhelming for the person, their families, caregivers and…

Catalyst Awardee

Study on Dietary Factors to Reduce Dementia Risk Related to Apolipoprotein E (ApoE) Genotype and Gender Difference (D-AGE)

Masahito Yamada, Ph.D., M.D., Kanazawa University; Tsuyoshi Hamaguchi, Ph.D., M.D., Kanazawa University; Moeko Noguchi-Shinohara, Ph.D., M.D., Kanazawa University;  Akihito Ishigami, Ph.D., Tokyo Metropolitan Institute of Gerontology
Competition Sponsor: Japan Agency for Medical Research and Development Major genetic risk factorsfor sporadic Alzheimer’s disease (AD) are “apolipoprotein E (ApoE) E4 (4 allele)”…

Catalyst Awardee

Toward Genetic Diagnosis of Sleep Characteristics in Each Individual: Identification of Sleepiness at the Cellular and Molecular Level in Mice

Yasutaka Niwa, Ph.D., M.D., University of Tsukuba
Competition Sponsor: Japan Agency for Medical Research and Development Despite the fact that sleep insufficiency is the cause of sleepiness and, eventually, various illnesses, no one knows what sleepiness is at the cellular and molecular level. If sleepiness in mice can be evaluated…


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