Ministry of Health and National Research Foundation of Singapore Archives - Page 3 of 5

Novel AI-driven ageing biomarker based on retinal photos for mortality risk stratification

Ching-Yu Cheng, MD, MPH, PhD; Tyler Hyungtaek Rim, MD, PhD, MBA; Yih Chung Tham, PhD; Simon Nusinovici, PhD
Competition Sponsor: Ministry of Health and National Research Foundation of Singapore
Awardee year: 2021 Globally, the number of persons aged 80 years or over is projected to increase more than threefold in…

Catalyst Awardee

Healthy living through personalized monitoring of eyelid care

Louis Tong, MBBS, FRCS(Ed), MD, FAMS, PhD; Ong Wai Sing
Competition Sponsor: Ministry of Health and National Research Foundation of Singapore
Awardee year: 2021 A lot of people with dry eye have significant discomfort, healthcare spending and time off work. A lot of this dry eye can be improved by…

Catalyst Awardee

Gamified fitness for healthy living

Yeo Joo Chuan, PhD; Wee Seng Kwee, PT, PhD
Competition Sponsor: Ministry of Health and National Research Foundation of Singapore
Awardee year: 2021 Sedentary lifestyle is the major risk factor for non-communicable diseases. While member states of World Health Organization have agreed to a 10% relative reduction in the prevalence…

Catalyst Awardee

Targeting SPTLC3-generated d16:1 sphingolipids for healthspan extension

Ong Wei Yi, BDS, PhD; Chester Drum, MD; Deron Herr, PhD Competition Sponsor: Ministry of Health and National Research Foundation of Singapore Age is the single most important factor that predicts risk of death due to diseases such as cancer, diabetes, and dementia. However, current medical approaches are designed to…

Catalyst Awardee

Development of miobiotics to maintain healthy ageing gut microbiota

Guan Shou Ping, PhD; Brian Kennedy, PhD Competition Sponsor: Ministry of Health and National Research Foundation of Singapore The human gut consists of both good bacteria that provide nutrients from indigestible sources and bad bacteria, which could lead to inflammatory and various disease states. The number of bad bacteria, however,…

Catalyst Awardee

Enhancing cognitive reserve in the community: Exploring the effects of Sensory Environment and Playfulness on Depression and Cognition (SEPDC) among older adults

Zdravko Trivic, PhD; Daniel R. Y. GAN, PhD; Habib Chaudhury, PhD; Patrick Dillon, PhD; Tam Elisabeth Perry, PhD

Competition Sponsor: Ministry of Health and National Research Foundation of Singapore In view of sensory and cognitive declines that advance with ageing, this interdisciplinary study aims to explore effects of Sensory Environment…

Catalyst Awardee

Identification of microRNA biomarkers in women predictive of reproductive senescence and longevity

Huang Zhongwei MBBS, PhD; Cheong Jit Kong, PhD
Competition Sponsor: Ministry of Health and National Research Foundation of Singapore Infertility affects ~15% of Singapore’s population. The number of couples in Singapore seeking assisted reproductive technology (ART) to help them conceive more than doubled from 2005-2013. With the median age at…

Catalyst Awardee

Characterizing the Role of Microglia-Mediated Cognitive Function in the Aging Brain

Thameem Dheen, Ph.D., and Jai S. Polepalli, M.A.S., Ph.D | National University of Singapore
Competition Sponsor: Ministry of Health and National Research Foundation of Singapore
Awardee Year: 2020 With a rapidly aging population, an increase in frequency of individuals with cognitive dysfunction and progressive deterioration of memory, represent an enormous…

Catalyst Awardee

Deciphering Aging-Dependent Human Neuronal Activity Changes, Tissue Microenvironment and Gene Expression Patterns

Jai S. Polepalli, M.A.S., Ph.D. | National University of Singapore; Thameem Dheen, Ph.D. | National University of Singapore; Vincent Nga Diong Weng, M.B.B.S., M.R.C.S., F.R.C.S.Ed (Surgical Neurology) | National University Hospital; and Yeo Tseng Tsai, M.B.B.S. | Fellowship of Royal Australasian College of Surgeons (Neurosurgery), National University …

Catalyst Awardee

Detecting Parkinson’s Disease-Associated Metabolites with Colorimetric Sensor Array and Machine Learning

Koh Tong Wey, M.Sc., Ph.D., and Ian Cheong, LL.B., Ph.D. | Temasek Life Sciences Laboratory; and Tan Eng Kind, M.B.B.S. | National Neuroscience Institute
Competition Sponsor: Ministry of Health and National Research Foundation of Singapore
Awardee Year: 2020 Parkinson’s disease (PD) is a common aging-related debilitating neurological disorder. No…

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