Research Grants Council of the Hong Kong Special Administrative Region, China Archives

Engineered osteochondral tissue (eOCT) as advanced therapeutic treatment for osteoarthritis (OA)

Barbara Chan, PhD | The University of Hong Kong; Patrick Shu-Hang YUNG FRCS; Chun Hoi Yan FRCS; Michael Tim-Yun Ong FRCS
Competition Sponsor: Research Grants Council of the Hong Kong Special Administrative Region, China Osteoarthritis (OA) is among the most prevalent degenerative disorders in aged populations worldwide. It affects…

Catalyst Awardee

Development of Small-Molecule Modulators of the Secretin Receptor as Novel Anti-Hypertensive Agents

Billy K.C. Chow, Ph.D. | The University of Hong Kong
Competition Sponsor: Research Grants Council of the Hong Kong Special Administrative Region, China
Awardee year: 2022 Large segments of aging hypertensive patients are resistant to a wide range of conventional drugs and hence there is an urgent need for…

Catalyst Awardee

AI-driven causal model to determine upstream definitive genetic biomarkers for early detection of Late Onset Alzheimer’s Disease

Victor OK Li, ScD | The University of Hong Kong ; Jacqueline CK Lam, PhD (Co-Lead); Illana Gozes, PhD; Jocelyn Downey, PhD
Competition Sponsor:Research Grants Council of the Hong Kong Special Administrative Region, China
Award year: 2022 Alzheimer’s disease (AD) is a leading cause of death in China and…

Catalyst Awardee

Empowering Acoustic Sensing and Learning on Accessible Speakers to Monitor and Detect Older Adult Falls

Chenshu Wu, PhD | The University of Hong Kong;
Competition Sponsor: Research Grants Council of the Hong Kong Special Administrative Region, China
Awardee year: 2022 Falls are the leading cause of accidental injury death worldwide for older adults. Globally, about 70 thousand fatal falls and over 37 million severe falls…

Catalyst Awardee

Bilobalide Derivatives as Therapeutics Against Ageing-Related Neurodegenerative Diseases

Billy Wai-Lung NG, Ph.D. | The Chinese University of Hong Kong; Kim Hei Man CHOW, Ph.D.; Owen Ho KO, Ph.D.
Competition Sponsor: Research Grants Council of the Hong Kong Special Administrative Region, China
Awardee year: 2022 Aging-related neurodegenerative diseases like Alzheimer’s disease are substantial medical and socioeconomic burdens…

Catalyst Awardee

Deciphering Disease Pathogenesis and Druggable Targets for Degenerative Tendinopathy using an Unbiased, Genome-wide, Single-Cell, Spatial Transcriptomic Approach

Patrick Shu Hang YUNG, FRCSEd | Department of Orthopaedics and Trumatology, The Chinese University of Hong Kong; Pauline Po Yee LUI, PhD
Competition Sponsor: Research Grants Council of the Hong Kong Special Administrative Region, China
Awardee year: 2022 Degenerative tendinopathy is a chronic musculoskeletal disorder presented with local tendon pain,…

Catalyst Awardee

Intelligent ultrasonic assessment of muscle quality for a functionally healthy elderly life

Wei-Ning Lee, PhD | The University of Hong Kong; Jinping Dong, PhD; Haotian Guan, MS
Competition Sponsor: Research Grants Council of the Hong Kong Special Administrative Region, China
Awardee year: 2022 Maintaining functional ability is central to physical and mental well-being in older age. Motility, which is endowed by…

Catalyst Awardee

Swallowable Encapsuled Multi-Stable Intragastric Balloons for Obesity Treatment (SEMIBOT)

Hongliang REN, PhD | The Chinese University of Hong Kong;
Competition Sponsor: Research Grants Council of the Hong Kong Special Administrative Region, China
Awardee year: 2022 Global obesity has increased at an alarming rate and has become an increasingly serious threat to public health and longevity, as declared by…

Catalyst Awardee

A novel human cellular system for studying normal ageing and for anti-ageing drug screen

Professor Pentao Liu, PhD | The University of Hong Kong; Shuofeng Yuan, PhD; Degong Ruan, PhD; Zhuoxuan Li, BSc.
Competition Sponsor: Research Grants Council of the Hong Kong Special Administrative Region, China
Awardee year: 2022 Ageing is a natural process, but healthy ageing and longevity can help alleviate the…

Catalyst Awardee

Senolytic uPAR-CAR-T therapy for osteoarthritis

Chunyi Wen, PhD | The Hong Kong Polytechnic University; Shenzhen University; Li Yu, MD, PhD; Chuan Yu, MS,
Competition Sponsor: Research Grants Council of the Hong Kong Special Administrative Region, China
Awardee year: 2022 The prerequisite of healthy longevity is the prevention and treatment of age-related diseases. However, pro-inflammatory…

Research Grants Council of the Hong Kong Special Administrative Region, China

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