Winners

Eliminating mutated mitochondrial DNA with modified nucleic acids

Catalyst Awardee

Joseph Baur, PhD| University of Pennsylvania
Competition Sponsor: US National Academy of Medicine
Awardee Year: 2022 Mitochondria, the “powerhouses of the cell” contain their own genomes that are present in…

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Filter by Competition Sponsor Academia Sinica Chile Agencia Nacional de Investigacion y Desarrollo Chinese Academy Medical Sciences EIT Health Japan Agency for Medical Research and Development Ministry of Health and National Research Foundation of Singapore National Academy of Medicine Research Grants Council of the Hong Kong Special Administrative Region, China The Chinese University of Hong Kong and The University of Hong Kong U.S. National Institute on Aging, National Institutes of Health United Kingdom Research and Innovation

Year 2022 2021 2020

Catalyst Awardee

Granulocyte Colony Stimulating Factor: A Novel Agent for Reproductive Longevity and Equality

Leslie Coker Appiah, MD| The University of Colorado Anschutz Medical Campus; Benjamin Bitler, PhD

Competition Sponsor: US National Academy of Medicine
Awardee Year: 2022

Advancements in cancer therapies have resulted in a sharp reduction in cancer mortality rates. However, lifesaving cancer treatments can jeopardize a woman’s reproductive longevity and impair

…

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Catalyst Awardee

Rebuilding the Health Workforce in Africa to Care for an Aging Population

Dr. Vanessa Kerry, MD, MSc. | Seed Global Health

Competition Sponsor: US National Academy of Medicine
Awardee Year: 2022

Africa’s elderly population is expected to grow faster than in any other region in the world, with a projected threefold increase by 2050. An aging population is accompanied by a shift

…

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Catalyst Awardee

Bridging the Gap between Postpartum and Primary Care: Novel Approaches to Care Continuity for Women at High Risk for Chronic Disease

Jessica Cohen, PhD | Harvard T. H. Chan School of Public Health; Mark Clapp, MD, MPH | Massachusetts General Hospital and Harvard Medical School

Competition Sponsor: US National Academy of Medicine
Awardee Year: 2022

Primary care providers (PCPs) are essential for prevention and management of chronic diseases across the lifespan.

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Catalyst Awardee

Development of a next-generation pharmaceutical to target oxidized cholesterol and reverse cardiovascular disease

Matthew S. O’Connor, PhD | Cyclarity Therapeutics

Competition Sponsor: US National Academy of Medicine
Awardee Year: 2022

Toxic oxysterols have been tied to numerous age-related diseases. Our team of scientists has engineered a custom cyclodextrin (a cyclic polysaccharide), which is designed to extract these toxic biomolecules from the body. We

…

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Catalyst Awardee

A new strategy for trastuzumab resistance reversal in breast cancer: Construction and application of a multifunctional nanomotor system combining RNAi therapy, starvation therapy, and microenvironmental oxygen supply therapy

Xiangyi Kong, MD. & PhD. | National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College; Jing Wang, MD. & PhD.; Yi Fang, MD. & PhD. ; Zhongzhao Wang, MD. & PhD; Xiangyu Wang, MD. & PhD; Wenxiang Zhang, MD.…

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Catalyst Awardee

Development and application of AI-assisted home skeletal muscle health exercise system for the elderly

Wang Zhong, M.M. | Beijing Tsinghua Changgung Hospital; Tiantongyuan North Community Healthcare Center; Wang Ziwen, M.M., Hu Kai，MBA, Wang Jingyi, M.M., Liu Wenbin, EMBA, Lin Baoliang, Bachelor Degree, Yang Kaiyue, M.M.
Competition Sponsor: Chinese Academy of Medical Sciences
Awardee Year: 2022   Aging is a normal physiological process in…

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Catalyst Awardee

Exercise and Brain Health: Pre-clinical Study of the Energy Transfer Hypothesis of Aging using PET/MRI imaging

Lauren Gerard Koch, PhD | The University of Toledo; Xin Yu, Sc.D. | Case Western Reserve University; Steven L. Britton, Ph.D. |  University of Michigan
Competition Sponsor: US National Academy of Medicine
Awardee Year: 2022 There is a strong link between high aerobic energy capacity and the increase in…

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Catalyst Awardee

Expanding a Multimodality VR Fitness Platform to Remotely Assess, Monitor, and Report Cognitive and Physical Function for Seniors

Jennifer J Stamps, PhD | Rendever; Kyle Rand, Co-founder/CEO, BS/BSE | Rendever
Competition Sponsor: US National Academy of Medicine
Awardee Year: 2022   As healthcare costs and the aging population increase, preventing the loss of cognitive and physical function is an urgent initiative. Social isolation increases the risk of…

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Catalyst Awardee

Monitoring of Alzheimer’s Disease Pathology Through Slow Wave Activity During Sleep in Older Adults

Makoto Kawai, MD | Division of Sleep Medicine, Department of Psychiatry and Behavioral Sciences, School of Medicine
Stanford University; Ada Poon, PhD |Department of Electrical Engineering, Stanford University
Competition Sponsor: US National Academy of Medicine
Awardee Year: 2022   It has been suggested that sleep can provide a…

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