Chun-Shu Wei, PhD |National Yang Ming Chiao Tung University
Competition Sponsor: Academia Sinica
Awardee Year: 2024
Major Depressive Disorder (MDD) significantly impacts individual well-being and societal productivity, posing a global health challenge with increasing economic costs. Treatment-resistant depression (TRD), affecting about 30% of MDD patients, fails to achieve remission with standard treatments. Current TMS approaches such as rTMS and iTBS suffer from limited efficacy due to their uniform application. Our project proposes a closed-loop, EEG-guided TMS system that personalizes brain stimulation by dynamically adjusting parameters using real-time EEG data and advanced deep learning techniques. This approach moves beyond the one-size-fits-all model, offering a cost-effective, high-compatibility solution for psychiatric clinics worldwide.