Catalyst Awardee

Project Description

Application value of electromagnetic navigation and CT guidance in thermal ablation of lung cancer: A prospective cohort study

Liang Zhao, M.M. | Cancer Hospital Chinese Academy of Medical Sciences;  Ruochuan Zang, M.D.; Hongliang Wu, M.D.; Wei Tang, M.M.; Lei Zhang, M.D.; Xiawu Zhang, M.D.; Xin Sun, M.M.; Fanmao Meng, M.B.
Competition Sponsor: Chinese Academy of Medical Sciences
Awardee Year: 2022

Lung cancer is a malignant tumor with the highest morbidity and mortality in China as well as the world. Although surgical resection is currently recognized as a radical cure for lung cancer, many patients with lung cancer have been found in the middle and late stage, or lost the opportunity for surgery due to other basic diseases, especially for elderly patients. Thermal ablation of tumor has become a good news for patients with tumor, the clinical development is rapid.
Before thermal ablation of lung cancer, CT guidance or bronchoscopy should be used for localization and biopsy specimens. In recent years, electromagnetic navigation bronchoscopy (ENB) combined with thermal ablation has become a new method for localization. There is still no clear conclusion and consensus on how to select appropriate ablation-assisted localization technology for patients with lung malignant tumor with different lesions location, number and imaging characteristics. Therefore, it is particularly important to evaluate new techniques for ENB or CT-guided thermal ablation of lung cancer.
In this study, we will choose patients with inoperable lung malignant tumor as the research object, after randomization respectively by ENB-guied or by CT-guied positioning, then follow-up, to assess the safety, effectiveness, economy and social adaptability of the two technologies, discusses indications of two kinds of treatment methods.

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