Catalyst Awardee

Project Description

Biomechanics and product development of a new spinal total cortical bone thread reducing screw for lumbar endoscopic fusion in elderly patients with osteoporosis

Paerhati Rexiti, PhD | Xinjiang Medical University; Weibin Sheng, PhD; Leilei Xu, MS; Shuiquan Wang, BM; Alafate Kahaer, MS; Dongshan Liu, MS; Xieraili Maimaiti, MS; Abulikemu Maimaiti, MS; Wenjie Shi, BM; Muzaipaer Maitusong, BM
Competition Sponsor: Chinese Academy of Medical Sciences
Awardee Year: 2022

Cortical bone trajectory (CBT), proposed by Santoni BG in 2009, increase the fixation strength without increasing the hospitalization cost and has become an ideal fixation method for the initial and revision of osteoporosis patients. We found that the traditional CBT technique needs to be further improved. Thus we proposed a modified cortical trajectory (MCBT) technique.
The traditional screw currently used in clinical practice cannot match our modified screw path, which may affect the biomechanical properties of the fixation to a certain extent. With the increasing demand of the elderly for the quality of life as traction, to solve the problem of postoperative failure of fixation in elderly patients with lumbar spinal stenosis and osteoporosis, we designed the combination of a new spinal total cortical bone thread reducing screw and 3D-navigation-template and endoscopy. Based on further realizing minimally invasive and accelerating the rehabilitation of elderly patients, the research results are put into practical application to solve clinical problems.
Through the combination of medicine and engineering, the biomechanical finite element model of lumbar osteoporosis was used to carry out mechanical experiments. The stress distribution between vertebral body and screw under different screws, different techniques, or their combinations under different loads was analyzed, and the factors affecting the stability of screw-bone interface and fatigue resistance were discussed. With the aid of a 3D navigation template and spinal endoscopy, the improvement of lumbar fusion surgery in lumbar spinal stenosis was tried to lay a foundation for its clinical application in patients with osteoporosis.


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