Huiping ZHANG | Beijing Hospital
Competition Sponsor: Chinese Academy of Medical Sciences
Awardee Year: 2024
Aortic Stenosis (AS) is a common valvular heart disease with a prevalence of 3% to 7% in the population over 65 years of age. In the elderly population, transcatheter aortic valve replacement (TAVR) has gradually become the standard alternative treatment for patients with severe AS who are at high surgical risk or have contraindications to surgical procedures. TAVR technology has become increasingly mature in China, but the aortic valve and perivalvular adjacent structures are complex. Considering the complexity of the aortic valve and perivalvular adjacent structures, the larger individual differences in the structure of the aortic root, and the complexity of the TAVR procedure, there are many uncertainties in the precise implementation of TAVR procedure, the evaluation of the postoperative outcome, and the prediction of perioperative complications.
This project is oriented to the clinical demand for simulation and accurate prediction of TAVR procedure in the elderly, to develop virtual simulation technology based on 3D printing and computational fluid dynamics, and to apply it in TAVR procedure, in order to guide the accurate implementation of TAVR procedure.