Daisuke Kokuryo, Ph.D. | Kobe University; Takashi Itahashi, Ph.D. | Showa University; Chika Sato, Ph.D. | National Institutes for Quantum and Radiological Science and Technology; Shigeyoshi Saito, Ph.D. | Osaka University
Competition Sponsor: Japan Agency for Medical Research and Development
Awardee Year: 2020

The proposed high-precision diagnostic and treatment evaluation technique aims to provide a quantitative evaluation that combines a harmonization technique across multiple imaging sites and scanners and a biological simulation technique based on the principle of Magnetic Resonance Imaging (MRI) for functional MRI (fMRI) data in order to compare past and present data, and use it as a reference point for future data. When the ideas presented in this proposal are implemented, the present fMRI data can be compared with past and future fMRI data quantitatively. As a contribution to the realization of a “society of health and longevity”, the proposed technique for the evaluation of the treatment effect and early prognostic prediction for mental and neurological disorders can be implemented rapidly and precisely. The extension of healthy life expectancy contributes to reducing the cost of treating and caring for patients in an aging society. Moreover, high-precision diagnosis and treatment prediction can be realized by only performing one test: an MRI.

To learn more about this proposal email healthylongevity@nas.edu.