Chuanhui Li, MD | Xuanwu Hospital of Capital Medical University; Xunming Ji, PhD & MD; Chuanjie Wu, MD; Longfei Wu, MD; Jian Chen, MD;Wenbo Zhao, MD
Competition Sponsor: Chinese Academy of Medical Sciences
Awardee Year: 2023
Stroke is a difficult to treat disease that seriously endangers human health and life safety in the world today. Acute ischemic stroke accounts for about 80% of all strokes, and the key to its treatment is to provide intravenous thrombolysis or endovascular thrombectomy as soon as possible after the attack and save the ischemic penumbra. Stroke caused by acute vertebrobasilar artery occlusion in the posterior circulation is the most severe type of ischemic stroke. If the occluded blood vessels cannot be reopened, the mortality rate and severe disability rate of patients are higher compared to those in the anterior circulation. However, for acute vertebrobasilar artery occlusion with large infarct core, it is currently uncertain whether endovascular therapy can achieve better prognosis compared to optimal medical treatment. This project aims to scientifically evaluate the safety and efficacy of endovascular treatment for acute vertebrobasilar artery occlusion patients with large infarct core through a prospective randomized controlled study.