Catalyst Awardee

Project Description

Exploration of Individualized Skull Base Reconstruction Strategy for Endoscopic Skull Base Tumor Surgery with the Goal of Fast Recovery

Pinan Liu, MD | Department of Neurosurgery, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China; Peng Li, MD; Zhijun Yang, MD; Bo Wang, MD; Xingchao Wang, MD; Zhenmin Wang, MD
Competition Sponsor: Chinese Academy of Medical Sciences
Awardee Year: 2022

With the aging trend becoming more and more obvious, skull base tumors have been found in more and more elderly people. Traditional craniotomy for resection of skull base tumors is traumatic and the therapeutic effect is not ideal. In the past 20 years, endoscopic technology has developed rapidly in neurosurgery, which can remove skull base tumors with minimal trauma and greatly reduce surgical trauma. After the operation, reliable skull base reconstruction is needed to properly protect the exposed skull base blood vessels and nerves, while tightly sealing the skull cavity to prevent postoperative cerebrospinal fluid leakage and intracranial infection. This is a critical step in endoscopic skull base surgery. At present, due to the limitation of surgical strategy, technique, equipment and material, the effect of skull base reconstruction in endoscopic surgery is not satisfactory, which is an important reason for serious postoperative complications and affecting the smooth rehabilitation after surgery. Systematically improving the level of endoscopic skull base reconstruction is the key to further improve the level of endoscopic skull base surgery. This project intends to establish a complete endoscopic skull base reconstruction system, improve the curative effect of endoscopic skull base surgery, reduce surgical complications and promote the rapid recovery of patients through (1) exploring and developing new skull base reconstruction technology represented by endoscopic skull base dural suture, (2) developing new skull base reconstruction instruments and materials, and (3) establishing and popularizing individualized endoscopic cranial base reconstruction strategies.


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