Yamako Go, PhD | University of Miyazaki; Chosa Etsuo, MD, PhD
Competition Sponsor: Japan Agency for Medical Research and Development
Awardee Year: 2024
A super-aging society must transition into a “healthy and longevity society” by addressing challenges related to bones, joints, and the musculoskeletal system. Osteoarthritis, a degenerative joint disease, causes pain, swelling, and stiffness, leading to restricted mobility. With aging populations, rising obesity, and increased injuries, the prevalence of osteoarthritis is expected to grow globally. However, effective treatments to prevent knee osteoarthritis are lacking, particularly after significant meniscal damage. We have developed the “float-ring”, an innovative implant designed to act as a cushion following partial or total meniscectomy, aiming to reduce knee pain and slow osteoarthritis progression. The meniscus, a fibrous cartilage, plays a vital role in load distribution and joint stability. When damaged, healing is limited to areas with blood supply, and sutures often result in unsatisfactory outcomes due to retears. In cases where suturing is not feasible, meniscal resection is performed, which can exacerbate cartilage damage and accelerate osteoarthritis. The float-ring is a non-absorbable, flexible implant that conforms to the joint surface during knee movement, reducing cartilage stress through effective load distribution. We believe that once fully developed, this implant will be a key innovation in promoting healthy longevity.