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Winners

Extracellular Vesicle (EV)-mediated Rescue of Immune Dysfunction and Cognitive Decline in Aging

Catalyst Awardee
Hiroshi Yamada, Ph.D., University of Tsukuba; Noga Ron-Harel, Ph.D., Israel Institute of Technology; Ayesha Saleem, Ph.D., University of Manitoba Competition Sponsor: Japan Agency for Medical Research and Development The aging…
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Catalyst Awardee

A Fully-implantable Wireless Brain Machine Interface for Functional Restoration

Masayuki Hirata, Ph.D., M.D., M.Eng., Osaka University; Hirsohi Yokoi, Ph.D., The University of Electro-Communications; Katsuyoshi Suzuki, M.Eng., Nihon Kohden Corporation; Jason Palmer, Ph.D., Ogino Memorial Laboratory
Competition Sponsor: Japan Agency for Medical Research and Development Physical disability due to various neurological diseases and spinal cord injuries enlarges dissociation between biological…
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Catalyst Awardee

Histone Modifications as New Targets for Pathophysiology of Accelerated Brain Aging Associated with Mental Disorders: Application for Development of Treatment and Diagnostic Method

Yuko Arioka, Ph.D., Nagoya University Hospital; Amrita Basu, Ph.D., University of California San Francisco; Simone Sidoli, Ph.D., Albert Einstein College of Medicine
Competition Sponsor: Japan Agency for Medical Research and Development Patients with mental disorders such as schizophrenia and bipolar disorder often die prematurely and are characterized by an overall…
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Catalyst Awardee

Identification of Biomarkers for Immune Ageing and Comprehensive Interventions for Age-related Disorders

Yoko Hamazaki, Ph.D., Kyoto University
Competition Sponsor: Japan Agency for Medical Research and Development Immunosenescence underlies increased lethal infection and inefficient vaccination efficiency in elderly people as well as various aging-associated chronic disorders after middle age. T cells play a central role in the immune system by promoting antibody production…
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Catalyst Awardee

Identification of Novel Lipid Species Generated by Autophagy that Promote Longevity

Shuhei Nakamura, Ph.D., Osaka University; Mark McCormick, Ph.D., University of New Mexico Health Sciences Center; Gareth Lim, Ph.D., Université de Montréal
Competition Sponsor: Japan Agency for Medical Research and Development Evolutionally-conserved molecular mechanisms that extend lifespan have been identified in model organisms, including yeast, worms, flies and mice. These include…
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Catalyst Awardee

Microbial Electricity Generation from Saliva Tells Your Oral Health Condition: Electrochemical Sensor Targeting Periodontal Pathogen in Saliva for the Longevity of Healthy Age

Akihiro Okamoto, Ph.D., National Institute of Materials Science; Tatsuji Nishihara, Ph.D., Kyushu Dental University; Gaku Imamura, Ph.D., National Institute of Materials Science
Competition Sponsor: Japan Agency for Medical Research and Development Oral infections such as periodontal disease and tooth decay cause various systemic diseases including dementia. With a technology that…
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Catalyst Awardee

Next-generation Medicine and Smart Health-care System for Prevention of Age-related Hearing Loss

Hiroshi Hibino, Ph.D., M.D., Niigata University; Satoyuki Kawano, Ph.D., Osaka University; Yoshiaki Kikkawa, Ph.D., Tokyo Metropolitan Institute of Medical Science
Competition Sponsor: Japan Agency for Medical Research and Development Numerous elder people are affected by “age-related hearing loss”. This irreversible disease not only serves as the greatest risk for developing…
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