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Winners

Extracellular Vesicle (EV)-mediated Rescue of Immune Dysfunction and Cognitive Decline in Aging

Catalyst Awardee
Hiroshi Yamada, Ph.D., University of Tsukuba; Noga Ron-Harel, Ph.D., Israel Institute of Technology; Ayesha Saleem, Ph.D., University of Manitoba Competition Sponsor: Japan Agency for Medical Research and Development The aging…
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Catalyst Awardee

A Fully-implantable Wireless Brain Machine Interface for Functional Restoration

Masayuki Hirata, Ph.D., M.D., M.Eng., Osaka University; Hirsohi Yokoi, Ph.D., The University of Electro-Communications; Katsuyoshi Suzuki, M.Eng., Nihon Kohden Corporation; Jason Palmer, Ph.D., Ogino Memorial Laboratory
Competition Sponsor: Japan Agency for Medical Research and Development Physical disability due to various neurological diseases and spinal cord injuries enlarges dissociation between biological…
Catalyst Awardee

Histone Modifications as New Targets for Pathophysiology of Accelerated Brain Aging Associated with Mental Disorders: Application for Development of Treatment and Diagnostic Method

Yuko Arioka, Ph.D., Nagoya University Hospital; Amrita Basu, Ph.D., University of California San Francisco; Simone Sidoli, Ph.D., Albert Einstein College of Medicine
Competition Sponsor: Japan Agency for Medical Research and Development Patients with mental disorders such as schizophrenia and bipolar disorder often die prematurely and are characterized by an overall…
Catalyst Awardee

Identification of Biomarkers for Immune Ageing and Comprehensive Interventions for Age-related Disorders

Yoko Hamazaki, Ph.D., Kyoto University
Competition Sponsor: Japan Agency for Medical Research and Development Immunosenescence underlies increased lethal infection and inefficient vaccination efficiency in elderly people as well as various aging-associated chronic disorders after middle age. T cells play a central role in the immune system by promoting antibody production…
Catalyst Awardee

Identification of Novel Lipid Species Generated by Autophagy that Promote Longevity

Shuhei Nakamura, Ph.D., Osaka University; Mark McCormick, Ph.D., University of New Mexico Health Sciences Center; Gareth Lim, Ph.D., Université de Montréal
Competition Sponsor: Japan Agency for Medical Research and Development Evolutionally-conserved molecular mechanisms that extend lifespan have been identified in model organisms, including yeast, worms, flies and mice. These include…
Catalyst Awardee

Microbial Electricity Generation from Saliva Tells Your Oral Health Condition: Electrochemical Sensor Targeting Periodontal Pathogen in Saliva for the Longevity of Healthy Age

Akihiro Okamoto, Ph.D., National Institute of Materials Science; Tatsuji Nishihara, Ph.D., Kyushu Dental University; Gaku Imamura, Ph.D., National Institute of Materials Science
Competition Sponsor: Japan Agency for Medical Research and Development Oral infections such as periodontal disease and tooth decay cause various systemic diseases including dementia. With a technology that…
Catalyst Awardee

Next-generation Medicine and Smart Health-care System for Prevention of Age-related Hearing Loss

Hiroshi Hibino, Ph.D., M.D., Niigata University; Satoyuki Kawano, Ph.D., Osaka University; Yoshiaki Kikkawa, Ph.D., Tokyo Metropolitan Institute of Medical Science
Competition Sponsor: Japan Agency for Medical Research and Development Numerous elder people are affected by “age-related hearing loss”. This irreversible disease not only serves as the greatest risk for developing…

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