Winners

Deciphering Aging-Dependent Human Neuronal Activity Changes, Tissue Microenvironment and Gene Expression Patterns

Catalyst Awardee

Jai S. Polepalli, M.A.S., Ph.D. | National University of Singapore; Thameem Dheen, Ph.D. | National University of Singapore; Vincent Nga Diong Weng, M.B.B.S., M.R.C.S., F.R.C.S.Ed (Surgical Neurology) |…

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Filter by Competition Sponsor Academia Sinica Agencia Nacional de Investigacion y Desarollo de Chile Chinese Academy of Medical Sciences EIT Health Japan Agency for Medical Research and Development Ministry of Health and National Research Foundation of Singapore National Academy of Medicine Research Grants Council of the Hong Kong Special Administrative Region, China The Chinese University of Hong Kong and The University of Hong Kong U.S. National Institute on Aging, National Institutes of Health United Kingdom Research and Innovation

Year 2023 2022 2021 2020

Catalyst Awardee

Detecting Parkinson’s Disease-Associated Metabolites with Colorimetric Sensor Array and Machine Learning

Koh Tong Wey, M.Sc., Ph.D., and Ian Cheong, LL.B., Ph.D. | Temasek Life Sciences Laboratory; and Tan Eng Kind, M.B.B.S. | National Neuroscience Institute
Competition Sponsor: Ministry of Health and National Research Foundation of Singapore
Awardee Year: 2020 Parkinson’s disease (PD) is a common aging-related debilitating neurological disorder. No…

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Catalyst Awardee

Enhanced Single Cell Transcriptomics for New Biomarkers and Targets in Cardiovascular Ageing

Roger Foo, M.B.B.S., M.R.C.P., M.D., C.C.S.T., F.R.C.P, and Matthew Ackers-Johnson, Ph.D., M.Phil., M.Sci. | National University of Singapore
Competition Sponsor: Ministry of Health and National Research Foundation of Singapore
Awardee Year: 2020 Cardiovascular disease (CVD) is the primary cause of morbidity and mortality globally. Related annual US healthcare expenditure exceeds…

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Catalyst Awardee

Ergothioneine, the Lesser Known Longevity Nutrient

Irwin Kee Mun Cheah, Ph.D., Feng Lei, D.Phil., and Barry Halliwell, PhD, D.Sc. | National University of Singapore
Competition Sponsor: Ministry of Health and National Research Foundation of Singapore
Awardee Year: 2020 The naturally occurring thione, ergothioneine, accumulates in the human body at high concentrations primarily from diet. Studies suggest…

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Catalyst Awardee

Examining Evidence for Transmissible Alzheimer’s Disease

Ajay Sriram Mathuru, Ph.D., and Jan Gruber, M.Sc., Ph.D. | National University of Singapore
Competition Sponsor: Ministry of Health and National Research Foundation of Singapore
Awardee Year: 2020 Alzheimer’s Disease (AD) is known to develop among many individuals in an age dependent manner. A few genetic variants in enzymes or…

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Catalyst Awardee

Organismal Aging and Oxidants Beyond Macromolecules Damage

Marie-Veronique Clement, M.Sc., Ph.D., and Shazib Pervaiz, M.B.B.S., Ph.D. | National University of Singapore
Competition Sponsor: Ministry of Health and National Research Foundation of Singapore
Awardee Year: 2020 One prediction of the free radical theory of aging is that oxidative stress shortens organisms’ lifespan because of the damaging effect of…

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Catalyst Awardee

p75 Neurotrophin Receptors in Forebrain Medial Septum Mediate the Enhanced Experimental Chronic Pain in Aged Rodent?

Sanjay Khanna, M.Sc., Ph.D., and Low Chian Ming, M.Sc., Ph.D. | National University of Singapore
Competition Sponsor: Ministry of Health and National Research Foundation of Singapore
Awardee Year: 2020 This proposal tests the hypothesis that the p75 neurotrophin receptors (NTR) in the forebrain medial septum (MS) is a basis of…

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Catalyst Awardee

Personalizing Exercise for Enhancing Healthspan: Using Artificial Intelligence for N-of-1 Exercise Prescription

Goh Jor Ming, M.Sc., Ph.D., Brian Kennedy, Ph.D., and Dean Ho, M.Sc., Ph.D. | National University of Singapore
Competition Sponsor: Ministry of Health and National Research Foundation of Singapore
Awardee Year: 2020 Exercise exerts physiological effects on multiple organs and tissues and is a powerful “drug” that improves healthspan, depending…

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Catalyst Awardee

Small RNAs: Big Answers to Healthy Longevity?

Hataitip Tasena, M.Sc., Ph.D., Brian Kennedy, Ph.D., Yvonne Tay, Ph.D., and Maximilian Unfried, M.Sc. | National University of Singapore
Competition Sponsor: Ministry of Health and National Research Foundation of Singapore
Awardee Year: 2020 Humans have long been searching for the path to longevity. Among the latest but less known possibilities…

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Catalyst Awardee

Studying Epigenetic Ageing and Telomere Length as Possible Biological Predictors for Healthy Ageing – The Singapore Chinese Health Study

Rajkumar Dorajoo, PhD | Genome Institute of Singapore; Brian Kennedy, PhD | National University of Singapore; Heng Chew Kiat, PhD | National University of Singapore; Liu Jianjun, PhD, MS | Genome Institute of Singapore; and Woon-Puay Koh, MBBS (Hons), PhD, FAMS | Duke-NUS Medical School
Competition…

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