Winners

Nanocatalysis for the Improvement of Human Healthspan and Lifespan

Catalyst Awardee

Karen Ho, PhD | Clene Nanomedicine Inc.
Competition Sponsor: National Academy of Medicine
Awardee Year: 2020 The remarkable property of metal-based nanoparticles to efficiently catalyze chemical reactions has been recognized…

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Filter by Competition Sponsor Academia Sinica Agencia Nacional de Investigacion y Desarollo de Chile Chinese Academy of Medical Sciences EIT Health Japan Agency for Medical Research and Development Ministry of Health and National Research Foundation of Singapore National Academy of Medicine Research Grants Council of the Hong Kong Special Administrative Region, China The Chinese University of Hong Kong and The University of Hong Kong U.S. National Institute on Aging, National Institutes of Health United Kingdom Research and Innovation

Year 2024 2023 2022 2021 2020

Catalyst Awardee

Paradigm Shift in the Molecular Transport to Brain Through the Direct Central Nerve-Innervation Based Retrograde Axonal Transport of Craniofacial Tissue Exosomes (RATCE)

Shigemi Ishikawa-Nagai, DMD, PhD, MSD | Harvard School of Dental Medicine; John da Silva, DMD, MPH, ScM | Harvard School of Dental Medicine; Albert Galaburda, MD | Harvard Medical School and Beth Israel Deaconess Medical Center; and Masazumi Nagai, DMD, PhD | Harvard School of Dental Medicine…

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Catalyst Awardee

Resilient Brains: New Insights for Healthy Brain Aging

Michael McConnell, PhD | Lieber Institute for Brain Development; Daniel R. Weinberger, MD |  Lieber Institute for Brain Development and Johns Hopkins University School of Medicine; and Thomas M. Hyde, MD, PhD | Lieber Institute for Brain Development and Johns Hopkins University School of Medicine
Competition Sponsor:…

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Catalyst Awardee

Retinal Imaging for Diagnosis of Aging-Related Brain Disorders

Alessandro Biffi, MD | Massachusetts General Hospital, Harvard University Medical School | Elena Z. Biffi, OD, MSc | New England College of Optometry; and Michael G. Morley, MD, ScM | Ophthalmic Consultants of Boston, Massachusetts Eye and Ear Infirmary, Harvard Medical School
Competition Sponsor: National Academy of Medicine
Awardee…

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Catalyst Awardee

Virtually Young: Can Embodying an Avatar of Your Younger Self Extend Your Healthy Lifespan?

Alexandra Ivanovitch, PhD | Equity Lab Global
Competition Sponsor: U.S. National Academy of Medicine
Awardee Year: 2020 One in four older adults experiences some mental disorder such as depression, anxiety, and dementia. This number is expected to double to 15 million by 2030 (National Council on Aging). We will design,…

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Catalyst Awardee

Characterizing the Role of Microglia-Mediated Cognitive Function in the Aging Brain

Thameem Dheen, Ph.D., and Jai S. Polepalli, M.A.S., Ph.D | National University of Singapore
Competition Sponsor: Ministry of Health and National Research Foundation of Singapore
Awardee Year: 2020 With a rapidly aging population, an increase in frequency of individuals with cognitive dysfunction and progressive deterioration of memory, represent an enormous…

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Catalyst Awardee

Deciphering Aging-Dependent Human Neuronal Activity Changes, Tissue Microenvironment and Gene Expression Patterns

Jai S. Polepalli, M.A.S., Ph.D. | National University of Singapore; Thameem Dheen, Ph.D. | National University of Singapore; Vincent Nga Diong Weng, M.B.B.S., M.R.C.S., F.R.C.S.Ed (Surgical Neurology) | National University Hospital; and Yeo Tseng Tsai, M.B.B.S. | Fellowship of Royal Australasian College of Surgeons (Neurosurgery), National University …

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Catalyst Awardee

Detecting Parkinson’s Disease-Associated Metabolites with Colorimetric Sensor Array and Machine Learning

Koh Tong Wey, M.Sc., Ph.D., and Ian Cheong, LL.B., Ph.D. | Temasek Life Sciences Laboratory; and Tan Eng Kind, M.B.B.S. | National Neuroscience Institute
Competition Sponsor: Ministry of Health and National Research Foundation of Singapore
Awardee Year: 2020 Parkinson’s disease (PD) is a common aging-related debilitating neurological disorder. No…

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Catalyst Awardee

Enhanced Single Cell Transcriptomics for New Biomarkers and Targets in Cardiovascular Ageing

Roger Foo, M.B.B.S., M.R.C.P., M.D., C.C.S.T., F.R.C.P, and Matthew Ackers-Johnson, Ph.D., M.Phil., M.Sci. | National University of Singapore
Competition Sponsor: Ministry of Health and National Research Foundation of Singapore
Awardee Year: 2020 Cardiovascular disease (CVD) is the primary cause of morbidity and mortality globally. Related annual US healthcare expenditure exceeds…

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Catalyst Awardee

Ergothioneine, the Lesser Known Longevity Nutrient

Irwin Kee Mun Cheah, Ph.D., Feng Lei, D.Phil., and Barry Halliwell, PhD, D.Sc. | National University of Singapore
Competition Sponsor: Ministry of Health and National Research Foundation of Singapore
Awardee Year: 2020 The naturally occurring thione, ergothioneine, accumulates in the human body at high concentrations primarily from diet. Studies suggest…

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