Rodrigo Valdoleiros e Silva, MD | Orgavalue
Competition Sponsor: EIT Health of the European Union
Awardee Year: 2023
Introducing Orgavalue, a revolutionary bioengineering marvel poised to transform the landscape of personalized human organ generation. Our state-of-the-art technology draws inspiration from evolutionary biology, culminating in the creation of intricately detailed human native-like organ scaffolds through cutting-edge decellularization techniques. These meticulously fashioned scaffolds serve as the canvas upon which our innovation truly shines. By introducing organ-specific human cells, we harness the innate adaptability of these cells, allowing them to seamlessly integrate, adhere, and thrive within our bioengineered structures. This harmonious amalgamation ensures the optimal functionality and immunogenicity of the resulting organs. While our primary focus lies in the creation of personalized livers, the potential to bioengineer lungs, pancreases, hearts, and kidneys, and potentially other internal organs promising a comprehensive solution to the dire scarcity of transplantable organs. One of the hallmarks of our approach lies in the prevention of adverse reactions and post-transplant rejections. This results in not only enhanced compatibility but also a significant reduction in organ wastage. Perhaps most strikingly, our groundbreaking process is executed within a remarkably swift timeframe. This efficient yet highly effective method stands as a beacon of hope for the countless patients across the globe who face the harrowing prospects of life without organ transplantation. Orgavalue stands as a testament to the remarkable achievements that emerge at the intersection of cutting-edge science, precision engineering, and compassionate healthcare solutions. With its potential to revolutionize organ transplantation, Orgavalue paves the way for a brighter, healthier future for individuals worldwide.